RNA - Ligand Interactions, Part A: Structural Biology Methods: Structural Biology Methods Gerald P. the linearized bifurcation and second-order

the linearized bifurcation and second-order large deflection are compared and the detailed procedure for a second-order analysis based on the Newton-Raphson scheme is described

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RNA - Ligand Interactions, Part A: Structural Biology Methods: Structural Biology Methods Gerald P. the linearized bifurcation and second-orderRNA Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X ray crystallography, NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology,